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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight reduction in addition to a reduced-calorie diet and physical exercise.
Using two separate drugs to lose weight naturally can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err to the side of caution and let the FDA do its job and demand some investigation be done so the public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to generate income and that they would say everything to keep people on his or her medications.
Researchers discovered that participants investing in this drug for a year, lost excess weight within one month and have kept the load off through the entire 56 weeks of the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs that are made up of many active ingredient, which can make them more potent and safer.
Combo-pilling will be the newest fad or in addition to this the newest in the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that by right now there aren't long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA.
Seizures can be a side effect with Contrave and must not be taken in people with seizure disorders. The drug can also raise blood pressure levels and heartrate, and must not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not used in patients with uncontrolled high blood pressure level, and also by you are not heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients for the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.
"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.